Genomically encoded analog memory with precise in vivo DNAwriting in living cell populations
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چکیده
, (2014); 346 Science Fahim Farzadfard and Timothy K. Lu writing in living cell populations Genomically encoded analog memory with precise in vivo DNA This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission to republish or repurpose articles or portions of articles ): November 13, 2014 www.sciencemag.org (this information is current as of The following resources related to this article are available online at http://www.sciencemag.org/content/346/6211/1256272.full.html version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/content/suppl/2014/11/12/346.6211.1256272.DC1.html can be found at: Supporting Online Material http://www.sciencemag.org/content/346/6211/1256272.full.html#related found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.sciencemag.org/content/346/6211/1256272.full.html#ref-list-1 , 29 of which can be accessed free: cites 61 articles This article http://www.sciencemag.org/content/346/6211/1256272.full.html#related-urls 1 articles hosted by HighWire Press; see: cited by This article has been http://www.sciencemag.org/cgi/collection/molec_biol Molecular Biology subject collections: This article appears in the following
منابع مشابه
Synthetic biology. Genomically encoded analog memory with precise in vivo DNA writing in living cell populations.
Cellular memory is crucial to many natural biological processes and sophisticated synthetic biology applications. Existing cellular memories rely on epigenetic switches or recombinases, which are limited in scalability and recording capacity. In this work, we use the DNA of living cell populations as genomic "tape recorders" for the analog and distributed recording of long-term event histories....
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